When is MLB Opening Day? Full schedule for three days of 2026 openers

Major League Baseball's opening games have taken different forms in recent years but this season will feature a semi-traditional standalone Opening Night game, with something of a twist – the first game of the 2026 regular season will air on Netflix.

The San Francisco Giants host the New York Yankees at Oracle Park on Wednesday, March 25, a matchup between two of the game's blue-blood franchises whose rivalry dates back more than 100 years – including seven meetings in the World Series.

Thursday, March 26 is a more traditional Opening Day, with 13 games and 26 teams playing their first contents of the season. The Toronto Blue Jays and Athletics play their first games of 2026 on Friday, one of eight games including the second meeting between the Giants and Yankees.

Winner of the past two World Series, the Los Angeles Dodgers begin their title defense on Thursday at home against the Arizona Diamondbacks.

Here's a look at the schedule for the first three days of the 2026 campaign:

When is MLB Opening Day? 2026 schedule

Wednesday, March 25

• New York Yankees at San Francisco Giants (8:05 p.m. ET) – BUY TICKETS

Thursday, March 26

• Pittsburgh Pirates at New York Mets (1:15 p.m.) – BUY TICKETS
• Chicago White Sox at Milwaukee Brewers (2:10 p.m.) – BUY TICKETS
• Washington Nationals at Chicago Cubs (2:20 p.m.) – BUY TICKETS
• Minnesota Twins at Baltimore Orioles (3:05 p.m.) – BUY TICKETS
• Boston Red Sox at Cincinnati Reds (4:10 p.m.) – BUY TICKETS
• Los Angeles Angels at Houston Astros (4:10 p.m.) – BUY TICKETS
• Detroit Tigers at San Diego Padres (4:10 p.m.) – BUY TICKETS
• Texas Rangers at Philadelphia Phillies (4:15 p.m.) – BUY TICKETS
• Tampa Bay Rays at St. Louis Cardinals (4:15 p.m.) – BUY TICKETS
• Arizona Diamondbacks at Los Angeles Dodgers (8:30 p.m.) – BUY TICKETS
• Cleveland Guardians at Seattle Mariners (10:10 p.m.) – BUY TICKETS

Friday, March 27

• Yankees at Giants (4:35 p.m.)
• Athletics at Toronto Blue Jays (7:07 p.m.)
• Colorado Rockies at Miami Marlins (7:10 p.m.)
• Kansas City Royals at Atlanta Braves (7:15 p.m.)
• Angels at Astros (8:10 p.m.)
• Tigers at Padres (9:40 p.m.)
• Guardians at Mariners (9:40 p.m.)
• Diamondbacks at Dodgers (10:10 p.m.)