Eric Dane praised as 'heroic' in tributes from 'Euphoria,' 'Charmed' costars

Eric Dane's 35-year career in Hollywood has earned him many friends and admirers. And now, tributes are pouring in following his death at 53 years old.

The "Grey's Anatomy" star – who died Feb. 19, 10 months after he went public with his ALS diagnosis – is being remembered as a "heroic" figure who advocated for ALS research and for patients' access to treatment.

Here are the costars and other celebrities who are sharing their memories with Dane.

Eric Dane's 'Euphoria' family is 'heartbroken'

In a statement shared with USA TODAY, "Euphoria" creator Sam Levinson said, "I’m heartbroken by the loss of our dear friend Eric. Working with him was an honor. Being his friend was a gift."

He continued, "Eric's family is in our prayers. May his memory be for a blessing."

Maria Shriver vows to 'honor' Eric Dane's story with memoir

Maria Shriver, whose Penguin Random House imprint The Open Field is slated to publish Dane's memoir "Book of Days: A Memoir in Moments," remembered Dane as being a "heroic" advocate for ALS awareness.

"I'm heartbroken by this devastating news about Eric Dane. What a tragedy. He was so heroic the way he handled his diagnosis. He used his voice to let the world know what it was like living with ALS," she wrote in a social media post.

"I was honored he chose my publishing imprint to publish his memoir. He told me he wanted his family to know how much he loved them, and he wanted to leave them a story they could be proud of. My love goes out to his family, and to all those battling this cruel disease, as well as all those caring for someone battling it."

She concluded: "Godspeed, Eric. It was an honor to know you, and we will honor your story. ♥️"

'Charmed' costar Alyssa Milano opens up about Dane's 'mischief' and 'tenderness'

Alyssa Milano, who performed alongside Dane in the latter seasons of "Charmed" and dated him in the early 2000s, reflected on their long-term friendship in an Instagram post.

"I can't stop seeing that spark in Eric's eye right before he’d say something that would either make you spit out your drink or rethink your entire perspective. He had a razor-sharp sense of humor. He loved the absurdity of things. He loved catching people off guard," she wrote in her caption.

"And when it came to his daughters and Rebecca, everything in him softened. He carried them with him even in rooms where they weren’t present. You could see it in the way his voice changed when he said their names. A breathtakingly beautiful family," she added. "The spark. The mischief. The tenderness he kept guarded but never totally hidden."

She revealed that Dane had "convinced me to get my pixie cut and my nose piercing. He also was with me on the walk when we found Lucy, my beloved rescue chihuahua."

The actress ended her remembrance by writing, "He called me 'Milano,' as if it was the only part of my name that mattered. My heart is with the people who were lucky enough to be his home."

Eric Dane is gone 'too soon'

John Stamos took to Instagram to mourn a friend who is gone "too soon." He wrote, "RIP, Buddy. Me and @realericdane played brothers years ago in a beautiful movie called, Wedding Wars. Good guy. Too soon."

In his X post, Ashton Kutcher joked, "The Franklin strip fanatics fantasy football league will miss Mr. Eric Dane. We know you’ll be watching from the booth."

Taking on a more somber tone, he added, "Miss you, buddy. Let’s keep fighting the fight to solve ALS." The two starred in separate storylines in the 2010 romcom "Valentine's Day."

Paul Walter Hauser penned a short tribute to his former costar, writing, "We tried to book gigs, we tried to laugh at the pain and we tried to stay sober. I’m glad we got to play together in 'Americana.' I love you, man. I wish we had more time. Enjoy the arms of Father God. I’ll see you again."

Dane's "Bad Boys: Ride or Die" costar Martin Lawrence shared photos of the two together on set and wrote, "My condolences go out to the family of @realericdane 🙏🏾 I can tell you firsthand — solid brotha, true professional, and brought that presence every single time. Much love!"

Kevin McKidd applauds 'Grey's Anatomy' costar's 'natural charisma'

Kevin McKidd, who plays Dr. Owen Hunt on "Grey's Anatomy," called his on-screen moments with Dane "incredible."

"He had a natural charisma and comedic dead pan timing like no other. I was honored and blessed to get to work with him on this iconic show," McKidd said in a statement to USA TODAY.

He continued: "All of us at Grey's send our love and condolences to his family - he is a huge part of our show and always will be."

The two were castmates for several seasons of the medical drama's long-running history. Dane's character, Mark Sloan, was on the show from seasons 2 to 9, while McKidd joined in Season 5 and has remained a series regular.

Contributing: Anthony Robledo, USA TODAY